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Original Article
Characteristic Changes in Decidual Gene Expression Signature in Spontaneous Term Parturition
Haidy El-Azzamy, Andrea Balogh, Roberto Romero, Yi Xu, Christopher LaJeunesse, Olesya Plazyo, Zhonghui Xu, Theodore G. Price, Zhong Dong, Adi L. Tarca, Zoltan Papp, Sonia S. Hassan, Tinnakorn Chaiworapongsa, Chong Jai Kim, Nardhy Gomez-Lopez, Nandor Gabor Than
J Pathol Transl Med. 2017;51(3):264-283.   Published online February 22, 2017
DOI: https://doi.org/10.4132/jptm.2016.12.20
  • 12,838 View
  • 270 Download
  • 28 Web of Science
  • 25 Crossref
AbstractAbstract PDFSupplementary Material
Background
The decidua has been implicated in the “terminal pathway” of human term parturition, which is characterized by the activation of pro-inflammatory pathways in gestational tissues. However, the transcriptomic changes in the decidua leading to terminal pathway activation have not been systematically explored. This study aimed to compare the decidual expression of developmental signaling and inflammation-related genes before and after spontaneous term labor in order to reveal their involvement in this process.
Methods
Chorioamniotic membranes were obtained from normal pregnant women who delivered at term with spontaneous labor (TIL, n = 14) or without labor (TNL, n = 15). Decidual cells were isolated from snap-frozen chorioamniotic membranes with laser microdissection. The expression of 46 genes involved in decidual development, sex steroid and prostaglandin signaling, as well as pro- and anti-inflammatory pathways, was analyzed using high-throughput quantitative real-time polymerase chain reaction (qRT-PCR). Chorioamniotic membrane sections were immunostained and then semi-quantified for five proteins, and immunoassays for three chemokines were performed on maternal plasma samples.
Results
The genes with the highest expression in the decidua at term gestation included insulin-like growth factor-binding protein 1 (IGFBP1), galectin-1 (LGALS1), and progestogen-associated endometrial protein (PAEP); the expression of estrogen receptor 1 (ESR1), homeobox A11 (HOXA11), interleukin 1β (IL1B), IL8, progesterone receptor membrane component 2 (PGRMC2), and prostaglandin E synthase (PTGES) was higher in TIL than in TNL cases; the expression of chemokine C-C motif ligand 2 (CCL2), CCL5, LGALS1, LGALS3, and PAEP was lower in TIL than in TNL cases; immunostaining confirmed qRT-PCR data for IL-8, CCL2, galectin-1, galectin-3, and PAEP; and no correlations between the decidual gene expression and the maternal plasma protein concentrations of CCL2, CCL5, and IL-8 were found.
Conclusions
Our data suggests that with the initiation of parturition, the decidual expression of anti-inflammatory mediators decreases, while the expression of pro-inflammatory mediators and steroid receptors increases. This shift may affect downstream signaling pathways that can lead to parturition.

Citations

Citations to this article as recorded by  
  • Is human labor at term an inflammatory condition?
    Chandrashekara Kyathanahalli, Madeline Snedden, Emmet Hirsch
    Biology of Reproduction.2023; 108(1): 23.     CrossRef
  • CCL2: An important cytokine in normal and pathological pregnancies: A review
    Zhi Lin, Jia-Lu Shi, Min Chen, Zi-Meng Zheng, Ming-Qing Li, Jun Shao
    Frontiers in Immunology.2023;[Epub]     CrossRef
  • Proteomic profile of extracellular vesicles in maternal plasma of women with fetal death
    Dahiana M. Gallo, Wendy Fitzgerald, Roberto Romero, Nardhy Gomez-Lopez, Dereje W. Gudicha, Nándor Gábor Than, Mariachiara Bosco, Tinnakorn Chaiworapongsa, Eunjung Jung, Arun Meyyazhagan, Manaphat Suksai, Francesca Gotsch, Offer Erez, Adi L. Tarca, Leonid
    The Journal of Maternal-Fetal & Neonatal Medicine.2023;[Epub]     CrossRef
  • Downregulated INHBB in endometrial tissue of recurrent implantation failure patients impeded decidualization through the ADCY1/cAMP signalling pathway
    Hui Zhang, Zhilong Wang, Quan Zhou, Zhiwen Cao, Yue Jiang, Manlin Xu, Jingyu Liu, Jidong Zhou, Guijun Yan, Haixiang Sun
    Journal of Assisted Reproduction and Genetics.2023; 40(5): 1135.     CrossRef
  • Regulation of inflammatory genes in decidual cells: Involvement of the bromodomain and extra-terminal family proteins
    Sandeep Ajgaonkar, Jonathan J. Hirst, Mary Norris, Tamas Zakar, Giovanni Camussi
    PLOS ONE.2023; 18(3): e0280645.     CrossRef
  • Decidual cells and decidualization in the carnivoran endotheliochorial placenta
    Mónica Elizabeth Diessler, Rocío Hernández, Gimena Gomez Castro, Claudio Gustavo Barbeito
    Frontiers in Cell and Developmental Biology.2023;[Epub]     CrossRef
  • Further Evidence that an Episode of Premature Labor Is a Pathologic State: Involvement of the Insulin-Like Growth Factor System
    Priya Prasad, Roberto Romero, Tinnakorn Chaiworapongsa, Nardhy Gomez-Lopez, Anderson Lo, Jose Galaz, Andreea B. Taran, Eunjung Jung, Francesca Gotsch, Nandor Gabor Than, Adi L. Tarca
    Fetal Diagnosis and Therapy.2023; 50(4): 236.     CrossRef
  • Galectins-1, -3 and -9 Are Present in Breast Milk and Have a Role in Early Life Development
    Karla Rio-Aige, Marina Girbal, Marta Selma-Royo, Anna Parra-Llorca, Sonia González, Cecilia Martínez-Costa, Margarida Castell, María Carmen Collado, Francisco J. Pérez-Cano, María J. Rodríguez-Lagunas
    Nutrients.2022; 14(20): 4338.     CrossRef
  • The Expression of IL-1β Correlates with the Expression of Galectin-3 in the Tissue at the Maternal–Fetal Interface during the Term and Preterm Labor
    Nikola Jovic, Marija Milovanovic, Jovana Joksimovic Jovic, Marija Bicanin Ilic, Dejana Rakic, Vladimir Milenkovic, Bojana Stojanovic, Jelena Milovanovic, Aleksandar Arsenijevic, Nebojsa Arsenijevic, Mirjana Varjacic
    Journal of Clinical Medicine.2022; 11(21): 6521.     CrossRef
  • Galectin-1 and Galectin-9 Concentration in Maternal Serum: Implications in Pregnancies Complicated with Preterm Prelabor Rupture of Membranes
    Dorota Grażyna Boroń, Aleksy Świetlicki, Michał Potograbski, Grażyna Kurzawińska, Przemysław Wirstlein, Daniel Boroń, Krzysztof Drews, Agnieszka Seremak-Mrozikiewicz
    Journal of Clinical Medicine.2022; 11(21): 6330.     CrossRef
  • Placental galectins regulate innate and adaptive immune responses in pregnancy
    Orsolya Oravecz, Roberto Romero, Eszter Tóth, Judit Kapitány, Máté Posta, Dahiana M. Gallo, Simona W. Rossi, Adi L. Tarca, Offer Erez, Zoltán Papp, János Matkó, Nándor Gábor Than, Andrea Balogh
    Frontiers in Immunology.2022;[Epub]     CrossRef
  • Galectin-Levels Are Elevated in Infants Born Preterm Due to Amniotic Infection and Rapidly Decline in the Neonatal Period
    Kirstin Faust, Nancy Freitag, Gabriela Barrientos, Christoph Hartel, Sandra M. Blois
    Frontiers in Immunology.2021;[Epub]     CrossRef
  • Inflammatory Amplification: A Central Tenet of Uterine Transition for Labor
    Kelycia B. Leimert, Wendy Xu, Magdalena M. Princ, Sylvain Chemtob, David M. Olson
    Frontiers in Cellular and Infection Microbiology.2021;[Epub]     CrossRef
  • Medawar’s PostEra: Galectins Emerged as Key Players During Fetal-Maternal Glycoimmune Adaptation
    Ellen Menkhorst, Nandor Gabor Than, Udo Jeschke, Gabriela Barrientos, Laszlo Szereday, Gabriela Dveksler, Sandra M. Blois
    Frontiers in Immunology.2021;[Epub]     CrossRef
  • The Role of Decidual Subpopulations in Implantation, Menstruation and Miscarriage
    Joanne Muter, Chow-Seng Kong, Jan J. Brosens
    Frontiers in Reproductive Health.2021;[Epub]     CrossRef
  • Multiomic immune clockworks of pregnancy
    Laura S. Peterson, Ina A. Stelzer, Amy S. Tsai, Mohammad S. Ghaemi, Xiaoyuan Han, Kazuo Ando, Virginia D. Winn, Nadine R. Martinez, Kevin Contrepois, Mira N. Moufarrej, Stephen Quake, David A. Relman, Michael P. Snyder, Gary M. Shaw, David K. Stevenson, R
    Seminars in Immunopathology.2020; 42(4): 397.     CrossRef
  • Role of galectin-glycan circuits in reproduction: from healthy pregnancy to preterm birth (PTB)
    Sandra M. Blois, Stefan Verlohren, Gang Wu, Gary Clark, Anne Dell, Stuart M. Haslam, Gabriela Barrientos
    Seminars in Immunopathology.2020; 42(4): 469.     CrossRef
  • Functional changes in decidual mesenchymal stem/stromal cells are associated with spontaneous onset of labour
    Joan C Wijaya, Ramin Khanabdali, Harry M Georgiou, Maria I Kokkinos, Patrick F James, Shaun P Brennecke, Bill Kalionis
    Molecular Human Reproduction.2020; 26(8): 636.     CrossRef
  • Ageing in human parturition: impetus of the gestation clock in the decidua†
    Joan C Wijaya, Ramin Khanabdali, Harry M Georgiou, Bill Kalionis
    Biology of Reproduction.2020; 103(4): 695.     CrossRef
  • Cytotrophoblast extracellular vesicles enhance decidual cell secretion of immune modulators via TNF-alpha
    Sara K. Taylor, Sahar Houshdaran, Joshua F. Robinson, Matthew J. Gormley, Elaine Y. Kwan, Mirhan Kapidzic, Birgit Schilling, Linda C. Giudice, Susan J. Fisher
    Development.2020;[Epub]     CrossRef
  • A trypsin-based method for isolating leukocytes from human choriodecidua suitable for immunophenotyping and transcriptome studies
    Karla MacDonald-Ramos, Marcia Arenas-Hernandez, Ismael Mancilla-Herrera, Claudia Rangel-Escareño, Rodrigo Vega-Sanchez
    Immunobiology.2019; 224(1): 177.     CrossRef
  • Transcriptomic analysis of fetal membranes reveals pathways involved in preterm birth
    Silvana Pereyra, Claudio Sosa, Bernardo Bertoni, Rossana Sapiro
    BMC Medical Genomics.2019;[Epub]     CrossRef
  • Placental Galectins Are Key Players in Regulating the Maternal Adaptive Immune Response
    Andrea Balogh, Eszter Toth, Roberto Romero, Katalin Parej, Diana Csala, Nikolett L. Szenasi, Istvan Hajdu, Kata Juhasz, Arpad F. Kovacs, Hamutal Meiri, Petronella Hupuczi, Adi L. Tarca, Sonia S. Hassan, Offer Erez, Peter Zavodszky, Janos Matko, Zoltan Pap
    Frontiers in Immunology.2019;[Epub]     CrossRef
  • Amnion epithelial cell–derived exosomes induce inflammatory changes in uterine cells
    Emily E. Hadley, Samantha Sheller-Miller, George Saade, Carlos Salomon, Sam Mesiano, Robert N. Taylor, Brandie D. Taylor, Ramkumar Menon
    American Journal of Obstetrics and Gynecology.2018; 219(5): 478.e1.     CrossRef
  • Selective immuno-modulatory effect of prolactin upon pro-inflammatory response in human fetal membranes
    Pilar Flores-Espinosa, Eduardo Preciado-Martínez, Araceli Mejía-Salvador, Gabriela Sedano-González, Luisa Bermejo-Martínez, Adalberto Parra-Covarruvias, Guadalupe Estrada-Gutiérrez, Rodrigo Vega-Sánchez, Isabel Méndez, Braulio Quesada-Reyna, Andrea Olmos-
    Journal of Reproductive Immunology.2017; 123: 58.     CrossRef
Review
Galectins: Double-edged Swords in the Cross-roads of Pregnancy Complications and Female Reproductive Tract Inflammation and Neoplasia
Nandor Gabor Than, Roberto Romero, Andrea Balogh, Eva Karpati, Salvatore Andrea Mastrolia, Orna Staretz-Chacham, Sinuhe Hahn, Offer Erez, Zoltan Papp, Chong Jai Kim
J Pathol Transl Med. 2015;49(3):181-208.   Published online May 15, 2015
DOI: https://doi.org/10.4132/jptm.2015.02.25
  • 25,965 View
  • 270 Download
  • 48 Web of Science
  • 46 Crossref
AbstractAbstract PDF
Galectins are an evolutionarily ancient and widely expressed family of lectins that have unique glycan-binding characteristics. They are pleiotropic regulators of key biological processes, such as cell growth, proliferation, differentiation, apoptosis, signal transduction, and pre-mRNA splicing, as well as homo- and heterotypic cell-cell and cell-extracellular matrix interactions. Galectins are also pivotal in immune responses since they regulate host-pathogen interactions, innate and adaptive immune responses, acute and chronic inflammation, and immune tolerance. Some galectins are also central to the regulation of angiogenesis, cell migration and invasion. Expression and functional data provide convincing evidence that, due to these functions, galectins play key roles in shared and unique pathways of normal embryonic and placental development as well as oncodevelopmental processes in tumorigenesis. Therefore, galectins may sometimes act as double-edged swords since they have beneficial but also harmful effects for the organism. Recent advances facilitate the use of galectins as biomarkers in obstetrical syndromes and in various malignancies, and their therapeutic applications are also under investigation. This review provides a general overview of galectins and a focused review of this lectin subfamily in the context of inflammation, infection and tumors of the female reproductive tract as well as in normal pregnancies and those complicated by the great obstetrical syndromes.

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  • The functional roles of protein glycosylation in human maternal–fetal crosstalk
    Jiangming Zhong, Jianlin Li, Graham J Burton, Hannu Koistinen, Ka Wang Cheung, Ernest H Y Ng, Yuanqing Yao, William S B Yeung, Cheuk-Lun Lee, Philip C N Chiu
    Human Reproduction Update.2024; 30(1): 81.     CrossRef
  • Decreased Expression of Placental Proteins in Recurrent Pregnancy Loss: Functional Relevance and Diagnostic Value
    Eszter Tóth, Dániel Györffy, Máté Posta, Petronella Hupuczi, Andrea Balogh, Gábor Szalai, Gergő Orosz, László Orosz, András Szilágyi, Orsolya Oravecz, Lajos Veress, Sándor Nagy, Olga Török, Padma Murthi, Offer Erez, Zoltán Papp, Nándor Ács, Nándor Gábor T
    International Journal of Molecular Sciences.2024; 25(3): 1865.     CrossRef
  • Is human labor at term an inflammatory condition?
    Chandrashekara Kyathanahalli, Madeline Snedden, Emmet Hirsch
    Biology of Reproduction.2023; 108(1): 23.     CrossRef
  • Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology
    Zhengyuan Huang, Pei F. Lai, Alexander T. H. Cocker, Stuart M. Haslam, Anne Dell, Hugh J. M. Brady, Mark R. Johnson
    Biochemical Society Transactions.2023; 51(2): 639.     CrossRef
  • Placental galectins regulate innate and adaptive immune responses in pregnancy
    Orsolya Oravecz, Roberto Romero, Eszter Tóth, Judit Kapitány, Máté Posta, Dahiana M. Gallo, Simona W. Rossi, Adi L. Tarca, Offer Erez, Zoltán Papp, János Matkó, Nándor Gábor Than, Andrea Balogh
    Frontiers in Immunology.2022;[Epub]     CrossRef
  • Proteoglycans: Systems-Level Insight into Their Expression in Healthy and Diseased Placentas
    Orsolya Oravecz, Andrea Balogh, Roberto Romero, Yi Xu, Kata Juhasz, Zsolt Gelencser, Zhonghui Xu, Gaurav Bhatti, Roger Pique-Regi, Balint Peterfia, Petronella Hupuczi, Ilona Kovalszky, Padma Murthi, Adi L. Tarca, Zoltan Papp, Janos Matko, Nandor Gabor Tha
    International Journal of Molecular Sciences.2022; 23(10): 5798.     CrossRef
  • Evolution of Placental Hormones: Implications for Animal Models
    Anthony M. Carter
    Frontiers in Endocrinology.2022;[Epub]     CrossRef
  • Possible important roles of galectins in the healing of human fetal membranes
    Jia-Le Chen, Yu Chen, De-Xiang Xu, Dao-Zhen Chen
    Frontiers in Endocrinology.2022;[Epub]     CrossRef
  • Melatonin-Primed MSCs Alleviate Intrauterine Adhesions by Affecting MSC-Expressed Galectin-3 on Macrophage Polarization
    Qi Jiang, Jingman Li, Yuchen Pan, Jiali Wang, Jingjing Yang, Sunan Shen, Yayi Hou
    Stem Cells.2022; 40(10): 919.     CrossRef
  • Galectin-1 and Galectin-9 Concentration in Maternal Serum: Implications in Pregnancies Complicated with Preterm Prelabor Rupture of Membranes
    Dorota Grażyna Boroń, Aleksy Świetlicki, Michał Potograbski, Grażyna Kurzawińska, Przemysław Wirstlein, Daniel Boroń, Krzysztof Drews, Agnieszka Seremak-Mrozikiewicz
    Journal of Clinical Medicine.2022; 11(21): 6330.     CrossRef
  • Galectin-7 dysregulates renin-angiotensin-aldosterone and NADPH oxide synthase pathways in preeclampsia
    Ellen Menkhorst, Wei Zhou, Leilani Santos, Jian-Guo Zhang, Yves St-Pierre, Morag J. Young, Evdokia Dimitriadis
    Pregnancy Hypertension.2022; 30: 130.     CrossRef
  • A természetes ölősejtek szerepe az anyai-magzati immunhomeostasis fenntartásában
    Kornél Lakatos, Kevin M. Elias, Ross S. Berkowitz, Kathleen Hasselblatt, György Végh, Vilmos Fülöp
    Orvosi Hetilap.2022; 163(19): 734.     CrossRef
  • Galectin-1 expression in the serum and placenta of pregnant women with fetal growth restriction and its significance
    Xiao-Xiao Jin, Xiang Ying, Min-Yue Dong
    BMC Pregnancy and Childbirth.2021;[Epub]     CrossRef
  • Medawar’s PostEra: Galectins Emerged as Key Players During Fetal-Maternal Glycoimmune Adaptation
    Ellen Menkhorst, Nandor Gabor Than, Udo Jeschke, Gabriela Barrientos, Laszlo Szereday, Gabriela Dveksler, Sandra M. Blois
    Frontiers in Immunology.2021;[Epub]     CrossRef
  • Maternal serum galectin-1 and galectin-3 levels in pregnancies complicated with preterm prelabor rupture of membranes
    Başak Kaya, Uğur Turhan, Salim Sezer, Serdar Kaya, İsmail Dağ, Ahmet Tayyar
    The Journal of Maternal-Fetal & Neonatal Medicine.2020; 33(5): 861.     CrossRef
  • Galectin-1 ameliorates lipopolysaccharide-induced acute lung injury via AMPK-Nrf2 pathway in mice
    Xiao-Ting Huang, Wei Liu, Yong Zhou, Mei Sun, Hui-Hui Yang, Chen-Yu Zhang, Si-Yuan Tang
    Free Radical Biology and Medicine.2020; 146: 222.     CrossRef
  • Oral Administration of Fucoidan Can Exert Anti-Allergic Activity after Allergen Sensitization by Enhancement of Galectin-9 Secretion in Blood
    Masashi Mizuno, Kana Sakaguchi, Iwao Sakane
    Biomolecules.2020; 10(2): 258.     CrossRef
  • Different Expression Pattern of TIM-3 and Galectin-9 Molecules by Peripheral and Peritoneal Lymphocytes in Women with and without Endometriosis
    Matyas Meggyes, Laszlo Szereday, Noemi Bohonyi, Miklos Koppan, Sarolta Szegedi, Anna Marics-Kutas, Mirjam Marton, Anett Totsimon, Beata Polgar
    International Journal of Molecular Sciences.2020; 21(7): 2343.     CrossRef
  • Glycan characterization of pregnancy-specific glycoprotein 1 and its identification as a novel Galectin-1 ligand
    Mirian Mendoza, Dongli Lu, Angela Ballesteros, Sandra M Blois, Kelsey Abernathy, Chiguang Feng, Charles J Dimitroff, Jonathan Zmuda, Maria Panico, Anne Dell, Gerardo R Vasta, Stuart M Haslam, Gabriela Dveksler
    Glycobiology.2020; 30(11): 895.     CrossRef
  • Characterisation of endogenous Galectin-1 and -9 expression in monocyte and macrophage subsets under resting and inflammatory conditions
    Franziska Krautter, Carlota Recio, Mohammed T. Hussain, Danielle R. Lezama, Francesco Maione, Myriam Chimen, Asif J. Iqbal
    Biomedicine & Pharmacotherapy.2020; 130: 110595.     CrossRef
  • Role of galectin-glycan circuits in reproduction: from healthy pregnancy to preterm birth (PTB)
    Sandra M. Blois, Stefan Verlohren, Gang Wu, Gary Clark, Anne Dell, Stuart M. Haslam, Gabriela Barrientos
    Seminars in Immunopathology.2020; 42(4): 469.     CrossRef
  • Galectin-7 Impairs Placentation and Causes Preeclampsia Features in Mice
    Ellen Menkhorst, Wei Zhou, Leilani L. Santos, Sarah Delforce, Teresa So, Kate Rainczuk, Hannah Loke, Argyro Syngelaki, Swati Varshney, Nicholas Williamson, Kirsty Pringle, Morag J. Young, Kypros H. Nicolaides, Yves St-Pierre, Evdokia Dimitriadis
    Hypertension.2020; 76(4): 1185.     CrossRef
  • Increased placental expression of Placental Protein 5 (PP5) / Tissue Factor Pathway Inhibitor-2 (TFPI-2) in women with preeclampsia and HELLP syndrome: Relevance to impaired trophoblast invasion?
    Katalin Karaszi, Szilvia Szabo, Kata Juhasz, Peter Kiraly, Barbara Kocsis-Deak, Beata Hargitai, Tibor Krenacs, Petronella Hupuczi, Offer Erez, Zoltan Papp, Ilona Kovalszky, Nandor Gabor Than
    Placenta.2019; 76: 30.     CrossRef
  • Tacrolimus treatment for infertility related to maternal‐fetal immune interactions
    Koushi Yamaguchi
    American Journal of Reproductive Immunology.2019;[Epub]     CrossRef
  • Human trophoblast requires galectin-3 for cell migration and invasion
    Ž. Bojić-Trbojević, M. Jovanović Krivokuća, A. Vilotić, N. Kolundžić, I. Stefanoska, F. Zetterberg, U. J. Nilsson, H. Leffler, Lj. Vićovac
    Scientific Reports.2019;[Epub]     CrossRef
  • Pregnancy Galectinology: Insights Into a Complex Network of Glycan Binding Proteins
    Sandra M. Blois, Gabriela Dveksler, Gerardo R. Vasta, Nancy Freitag, Véronique Blanchard, Gabriela Barrientos
    Frontiers in Immunology.2019;[Epub]     CrossRef
  • Placental Galectins Are Key Players in Regulating the Maternal Adaptive Immune Response
    Andrea Balogh, Eszter Toth, Roberto Romero, Katalin Parej, Diana Csala, Nikolett L. Szenasi, Istvan Hajdu, Kata Juhasz, Arpad F. Kovacs, Hamutal Meiri, Petronella Hupuczi, Adi L. Tarca, Sonia S. Hassan, Offer Erez, Peter Zavodszky, Janos Matko, Zoltan Pap
    Frontiers in Immunology.2019;[Epub]     CrossRef
  • Galectin 13 (PP13) Facilitates Remodeling and Structural Stabilization of Maternal Vessels during Pregnancy
    Marei Sammar, Tijana Drobnjak, Maurizio Mandala, Sveinbjörn Gizurarson, Berthold Huppertz, Hamutal Meiri
    International Journal of Molecular Sciences.2019; 20(13): 3192.     CrossRef
  • Differential gene expression in bovine endometrial epithelial cells after challenge with LPS; specific implications for genes involved in embryo maternal interactions
    Yongzhi Guo, Tom van Schaik, Naveed Jhamat, Adnan Niazi, Metasu Chanrot, Gilles Charpigny, Jean Francois Valarcher, Erik Bongcam-Rudloff, Göran Andersson, Patrice Humblot, Peter J. Hansen
    PLOS ONE.2019; 14(9): e0222081.     CrossRef
  • The Impact of Natural Selection on the Evolution and Function of Placentally Expressed Galectins
    Zackery A Ely, Jiyun M Moon, Gregory R Sliwoski, Amandeep K Sangha, Xing-Xing Shen, Abigail L Labella, Jens Meiler, John A Capra, Antonis Rokas, Soojin Yi
    Genome Biology and Evolution.2019; 11(9): 2574.     CrossRef
  • Dysregulation of Placental Functions and Immune Pathways in Complete Hydatidiform Moles
    Jennifer R. King, Melissa L. Wilson, Szabolcs Hetey, Peter Kiraly, Koji Matsuo, Antonio V. Castaneda, Eszter Toth, Tibor Krenacs, Petronella Hupuczi, Paulette Mhawech-Fauceglia, Andrea Balogh, Andras Szilagyi, Janos Matko, Zoltan Papp, Lynda D. Roman, Vic
    International Journal of Molecular Sciences.2019; 20(20): 4999.     CrossRef
  • The emerging role of galectins in high-fatality cancers
    Cherylane Dubé-Delarosbil, Yves St-Pierre
    Cellular and Molecular Life Sciences.2018; 75(7): 1215.     CrossRef
  • Dissecting the Structure–Activity Relationship of Galectin–Ligand Interactions
    Yi-Chen Chan, Hsien-Ya Lin, Zhijay Tu, Yen-Hsi Kuo, Shang-Te Hsu, Chun-Hung Lin
    International Journal of Molecular Sciences.2018; 19(2): 392.     CrossRef
  • The link between immunity, autoimmunity and endometriosis: a literature update
    Tao Zhang, Caterina De Carolis, Gene Chi Wai Man, Chi Chiu Wang
    Autoimmunity Reviews.2018; 17(10): 945.     CrossRef
  • Systemic expression of galectin genes in periparturient goats
    Kingsley Ekwemalor, Sarah Adjei-Fremah, Emmanuel Asiamah, Egbogoye Eluka-Okoludoh, Bertha Osei, Mulumebet Worku
    Small Ruminant Research.2018; 168: 60.     CrossRef
  • Body Mass Index Impact and Predictability on Preeclamptic Toxemia
    AbdAllah Khaled M
    Journal of Gynecological Research and Obstetrics.2018; : 009.     CrossRef
  • The association between oxidative stress-induced galectins and differentiation of human promyelocytic HL-60 cells
    James R. Vinnai, Robert C. Cumming, Graham J. Thompson, Alexander V. Timoshenko
    Experimental Cell Research.2017; 355(2): 113.     CrossRef
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  • Intracellular galectin-7 expression in cancer cells results from an autocrine transcriptional mechanism and endocytosis of extracellular galectin-7
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    PLOS ONE.2017; 12(11): e0187194.     CrossRef
  • Serum galectin-9 as a noninvasive biomarker for the detection of endometriosis and pelvic pain or infertility-related gynecologic disorders
    Reka Brubel, Attila Bokor, Akos Pohl, Gabriella Krisztina Schilli, Laszlo Szereday, Reka Bacher-Szamuel, Janos Rigo, Beata Polgar
    Fertility and Sterility.2017; 108(6): 1016.     CrossRef
  • The relationship between cervical precancerous lesion galectin-3 and p27 protein expression and clinical prognosis
    Jianting Ma, Xingguang Zhang, Gang He, Chunlin Yang
    Oncology Letters.2017;[Epub]     CrossRef
  • Development and Applications of Lectins as Biological Tools in Biomedical Research
    Xiuli Dan, Wenlong Liu, Tzi Bun Ng
    Medicinal Research Reviews.2016; 36(2): 221.     CrossRef
  • The human fetoembryonic defense system hypothesis: Twenty years on
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    Molecular Aspects of Medicine.2016; 51: 71.     CrossRef
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